If you have been around here long enough, you know I am obsessed with cranberry anything. Whether it is sauce, bread, or drinks, I love the tartness and the color. When I realized I had a leftover can of cranberry sauce in the pantry, I decided to see if I could turn it into a high-protein breakfast.

These muffins are the result of that experiment. By combining a simple cake mix with protein powder and a full can of cranberry sauce, I ended up with a treat that packs 12g of protein and only 215 calories per muffin. They are tender, moist, and stay soft without any added oil or flour.
If you're looking for other Muffins hits, try my Peppermint Cottage Cheese Muffins, Maple Pumpkin Muffins Gluten Free Soft And Perfect For Fall, or Snickerdoodle Protein Muffins The 110 Calorie Gain Hack.
The Cranberry Emulsion Strategy
In traditional baking, you need fat (butter or oil) to coat flour proteins and create a soft crumb. In this recipe, the pectin and sugar structure of the cranberry sauce acts as the moisture-retaining agent. When you run this through a high-speed blender, you create a smooth emulsion that suspends the protein powder, preventing that “rubbery” texture often found in protein-heavy bakes.
Why You'll Love This Recipe
- Minimal Cleanup: You blend the entire batter in one jar—no bowls, no whisks, no mess.
- Superior Moisture: The cranberry sauce replaces oil entirely, keeping these muffins soft for days.
- Macro-Friendly: High protein content with zero added flour or fat, making it easy to hit your goals.
- Foolproof Texture: Using a blender ensures the protein powder is fully hydrated, eliminating grittiness.

Ingredient Deep Dive & Strategy
Large Eggs: Essential for binding the protein and providing the necessary lift.
Cranberry Sauce: This provides the bulk of the moisture and the primary flavor profile. Both jellied and whole berry work, though jellied provides a smoother texture.
PE Science Protein Powder: You must use a whey/casein blend like PE Science (Code: BAKEDLEAN). 100% whey protein tends to become rubbery and dry when baked. The addition of casein provides the structural integrity and “cake-like” crumb we want.
Sugar-Free Yellow Cake Mix: This provides the leavening agents and a base flavor that lets the cranberry shine.

What Protein Powder Works Best?
I've tested a lot of protein powders in baking, and the truth is: they're not all created equal. Some turn baked goods gritty. Some make everything dry. Some refuse to mix no matter what you do.
But PE Science?
That's the one I use in pretty much everything — and it always works.
Their whey + casein blend gives baked goods structure without drying them out, and it actually improves texture instead of destroying it. It mixes smoothly in the blender, the flavors hold up in heat, and it doesn't get that weird chalky thing that other powders do.
For these muffins, I used PE Science Vanilla because it blends perfectly with the cranberry and keeps the muffins light and soft.
If you want the exact protein powder I use every day in my recipes, grab it here:
PE Science (use code BakedLean for a discount!)
Cranberry Protein Muffins Ingredients
- 400g (1 can) Cranberry Sauce
- 215g (1/2 box) Sugar-Free Yellow Cake Mix
- 3 Large Eggs
- 90g (3/4 cup) PE Science Vanilla Protein Powder
- Optional: 15-30ml Water (if batter is too thick)
Step-By-Step Instructions (with tips)
Step 1 — Preheat your oven
Set the oven to 350°F (175°C) and grease or line a muffin tin.
You'll get 9 muffins, not 12.
Tip: Leaving 3 empty cups helps the muffins get taller domes.
Step 2 — Build your batter in the blender
Add your ingredients in this order:
- Eggs
- Cranberry sauce
- Cake mix
- Protein powder
Blend until smooth.
Tip:
If your blender looks like it's struggling or the batter is super thick (cranberry sauce varies), add a tablespoon or two of water or milk. Not too much.

Step 3 — Fill the muffin tin
Portion the batter evenly between 9 cups, about ¾ full.
Tip:
A large cookie scoop keeps everything even so they bake the same.

Step 4 — Bake
Bake for 25 minutes — don't go shorter.
Cranberry adds a lot of moisture, and these need time to set fully.
They should bounce back when pressed and look lightly golden.
Step 5 — Cool in the pan
Let them cool in the muffin tin for 15–20 minutes before removing.
Tip:
Protein muffins firm up as they cool, so don't skip this step.
Troubleshooting & FAQ
- Why are my muffins flat? This usually happens if the eggs were old or the blender introduced too much air, which then collapsed. Ensure your oven is fully preheated before the batter goes in.
- The center is mushy. Cranberries hold a lot of water. If the center is wet, they needed another 3-5 minutes. Every oven is different, so use a toothpick to check.
- Can I use fresh cranberries? No, fresh cranberries won't provide the same moisture or sweetness. This recipe specifically relies on the syrupy nature of canned sauce.
- Can I use 100% Whey? I don't recommend it. It will likely result in a rubbery, “bouncy” texture rather than a soft muffin.
- My batter won't blend. Always add the liquid components (eggs and sauce) to the blender first, then the dry powders on top.

Substitutions Table
| Component | Swap Options |
| Cranberry Sauce | Pumpkin Puree or Unsweetened Applesauce |
| Yellow Cake Mix | White Cake Mix or Spice Cake Mix |
| Protein Powder | Unflavored Whey/Casein (add 1 tsp Vanilla Extract) |
| Eggs | 3/4 cup Liquid Egg Whites |
Storage & Reheating
Store these in an airtight container in the fridge for up to 6 days. Because of the fruit moisture, they do best when kept cold. To reheat, microwave for 15 seconds or pop them in the air fryer at 300°F (150°C) for 3 minutes to restore the exterior texture.
You Might Also Like
- High Protein Orange Cranberry Biscotti Low Sugar No Oil
- Single Serve Cranberry Cottage Cheese Scone
- Kentucky Bourbon Cranberry Sauce
The Final Verdict & Share
These are the easiest muffins you will ever make. They prove that you don't need a pantry full of flours and oils to make something that tastes like a real treat. If you make these, tag me so I can see how they turned out!

Ultra Simple Cranberry Protein Muffins
Ingredients
- 1/2 box sugar-free yellow cake mix (approx. 7.5 oz / 215 g)
- 3/4 cup protein powder (vanilla or unflavored)
- 3 eggs
- 1 can cranberry sauce (14 oz / 400 g, no sugar added preferred)
- 1-2 tbsp water or milk optional, only if batter is too thick
- 1/2 tsp cinnamon or orange zest optional
Equipment
Method
- Preheat oven to 350°F (175°C). Line or grease a muffin tin. This recipe makes 9 muffins.

- Add eggs and cranberry sauce to the blender first. Then add cake mix and protein powder. Blend until completely smooth. Add 1–2 tbsp water or milk only if needed to loosen.

- Divide batter evenly into 9 muffin cups, filling each about 3/4 full.

- Bake for 25 minutes, or until tops are set and a toothpick comes out clean. These muffins need a full bake so they don't collapse.
- Cool muffins in the pan for 15–20 minutes to firm up before removing.

Nutrition
Video
@bakedlean ULTRA SIMPLE CRANBERRY PROTEIN MUFFINS Blender recipe. No oil. No flour. Just mix, pour, bake. Macros (per muffin): ~150 calories • 9g protein Ingredients ½ box sugar-free cake mix 2 scoops vanilla protein 1 can whole-berry cranberry sauce 2 eggs How to make Blend everything until smooth. Pour into a muffin tin. Bake at 350°F for about 25 minutes until set. Let cool so they don't collapse. Full recipe with step-by-step is on my website ⬇️ https://bakedlean.com/ultra-simple-cranberry-protein-muffins-blender-recipe/ #bakedlean #proteinmuffins #cranberryrecipes #highprotein #healthybaking
♬ original sound – BakedLean
Notes
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3 responses to “Cranberry Protein Muffins (High-Protein Recipe)”
easy and deliciousJacob, what is the dry ingredient in the bowl shown in the video when you're pouring in the blended batter. It appears to be cake mix, but the recipe directions have us putting all ingredients in the blender. Unless I'm not following along. Thanks!
I folded the wet ingredients in with the cake mix to not overwork the cake mix. But I edited the recipe to make it more simple and just put it all in the blender. I've done other muffins this way without issue.










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